UCLA
CHEMICAL
ENGINEERING




YI TANG


RECENT PAPERS

Kumar, P; Khosla, C; Tang, Y."Manipulation and analysis of polyketide synthases." Protein Eng., 388: 269-293 2004.

Tang, Y; Lee, TS; Lee, HY; Khosla, C. "Exploring the biosynthetic potential of bimodular aromatic polyketide synthases." Tetrahedron, 60 (35): 7659-7671 AUG 23 2004.

Tang, Y; Koppisch, AT; Khosla, C. "The acyltransferase homologue from the initiation module of the R1128 polyketide synthase is an acyl-ACP thioesterase that edits acetyl primer units." Biochemistry, 43 (29): 9546-9555 JUL 27 2004.

Tang, Y., S.C. Tsai and C. Khosla. "Polyketide Chain Length Control by Chain Length Factor." J. American Chemical Soc., 125(42):12708-12709 (Oct. 22, 2003).

Cirino, P. C., Y. Tang, K. Takahashi and D. A. Tirrell. "Global Incorporation of Norleucine in Place of Methionine in Cytochrome P450 BM-3 Heme Domain Increases Peroxygenase Activity." Biotechnology and Engineering, 83(6): 729-734 (Sep. 20, 2003).

Wang, P., Y. Tang and D. A. Tirrell. "Incorporation of Trifluoroisoleucine into Proteins in Vivo." J. American Chemical Soc., 125(23):6900-6906 (Jun 11, 2003).

Tang, Y., T. S. Lee, S. Koyabashi and C. Kholsa. "Ketosynthases in the Initiation and Elongation Modules of Aromatic Polyketide Synthases have Orthogonal Acyl Carrier Protein Specificity." Biochemistry, 42(21):6588-6595 (Jun. 3, 2003).

Tang Y. and D. A. Tirrell,  “Attenuation of Leucyl-tRNA Synthetase Proofreading Activity in Escherichia coli Allows Introduction of An Array of Unnatural Amino Acids in vivo.”  Biochemistry,  41, 10635-10645 (2002).

Tang Y. and D. A. Tirrell, "Biosynthesis of a Highly Stable Coiled-Coil Protein Containing Hexafluoroleucine in an Engineered Bacterial Host," J. American Chemical Soc., V123 (44), 11089-11090, (Nov. 7 2001)

Tang Y., G. Ghirlanda, W. A. Petka, T. Nakajima, W. F. DeGrado and D. A. Tirrell, “Fluorinated Coiled-Coil Proteins Prepared in Vivo Display Enhanced Thermal and Chemical Stability,” Angew. Chem. Int. Edit., V40 (8), 1494-1497, (2001).

Tang Y., G. Ghirlanda, N. Vaidehi, J. Kua, D. T. Mainz, W. A. Goddard III, W. F. DeGrado and D. A. Tirrell, “Stabilization of Coiled-Coil Peptide Domains by Introduction of Trifluoroleucine,” Biochemistry-US, V40 (9): 2790-2796 (Mar. 6 2001).

For more information, send mail to yitang@stanford.edu.

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